Then there were guinea pigs like these:
In March 2006, eight male volunteers checked into London's Northwick Park Hospital for a weeklong study of TGN1412, an experimental treatment for rheumatoid arthritis and leukemia to be manufactured by Boehringer-Ingelheim. Within minutes of receiving the first dose, six of them began to writhe in pain, vomit, and lose consciousness, according to news reports. Nurses rushed them to the hospital's trauma unit, where doctors treated them for multiple organ failure. The test subjects lived, but all suffered permanent damage to their immune systems and internal organs. One lost fingers and toes. Another developed signs of cancer possibly triggered by the drug.Read the fascinating article here.